Paget Disease is a chronic disorder of the bones that affects 1-3% of the population over age 50. It is characterized by an accelerated rate of bone remodeling, resulting in abnormal and weakened formation. This can lead to various skeletal deformities and increased fracture risk. Its pathophysiology involves excessive osteoclastic and osteoblastic activity, which results in abnormal bony structure with altered composition, causing thickening or enlargement of bones as well as unusual patterned areas on x-rays. The underlying cause of this process remains unknown but some research suggests it may be related to genetic predisposition, exposure to certain viruses, or a combination thereof.